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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35f91328db558f6013ec2c15fb350f1aed1b5aeb3fa875db2fdecf7f2d358dc' 
  AND token = 'BQ2D1r07acNQcI1ic8Vtc1cOfIyqXGEGWHk0DGhkFTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}