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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b57732429ed90000588239ebaf9b63e7b327b866c3fcc95f743c8f3a38ab24' 
  AND token = '+RDzuJwH00UN2IhU9Dtivfont5lNwDHVtQaMt2W67MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}