SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d177100859765a359d3a13ddd3ea363a6991744f7f453184fb653ba556f4526' 
  AND token = 'SGL1vhkFlERoEx0dOJlbMwttlkAR3tnu++xfNr7uWEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}