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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665be8d4cfb52cae7b17c56d6f8e79cb5db2b25ff77abb522e5ade252306e209' 
  AND token = 'mAO++Hv1SbuP+8U+fkPcghbDFnqyZS0+ul9N467VD7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}