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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd9cbe5b551b7809d150f992c58219b1451b425b0887a304ec35461837ac764a' 
  AND token = 'zwLnQIVT8wsUH9UOx/bkrCArJte3hpv2u9Ri1IrgCn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}