SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23397d32db182614c8b3313db2d01540ab6e483f5bfa6693166626761608eb22' 
  AND token = '0xAKRPmdCDiwji9Sibf7ddRG3I5ApZgzZ33mHWa7zSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}