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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1c22f4b0d9c5ad94bd1243c6294722d3af6ca7f9ace4a7e7afb331c04bba4d' 
  AND token = 'iNVkVBbwthnwV9VXFE+95Qm/Uhw5Dzrq+hAWZ9dSHDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}