SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27033c47296d031741d3bde3157d7fc18dc1c75d9235e5e2ca5d4a312822006' 
  AND token = '+9z/Oc1CRGwUvwwZK04COq3UxTWK0LmsBlb2kWXEwWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}