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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f9e52e2e4d557912dc289a81de2c6b7dc454a86eb900444e7df177d4adb951' 
  AND token = 'siS0V7592M7Qxsew6WyMJKDKqtxbj0hXo7XLA09rUjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}