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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251dc316fd78d7580122ed1773e223b5930c79d82f7d26a2a7f8b0349b776a0f' 
  AND token = 'otsCUi2/VG0y9gdc+wZhmeDTsPIg2oWDfR1PJnNIP7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}