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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426c3c7188ad5854f6d8357fc25cc52e3cc3ccc9629f43889d6e3b2a15e83a5d' 
  AND token = 'CFRXT9CZS9v5svImH5Y9Twq9QbdyAJgSLDK4Fut9DBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}