SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ac53d5546b59ad868144c089443b071fdabef8d01ff5d2a47f4c22ef9e17fe2' 
  AND token = 'C4Q1iYJMt1qa/K9SH4WwzbdHVCLh2TSDZB7zlbGwQsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}