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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d8a65afe852941f2c38e28ce89118317d53a9b7d40ef2a07759ffed9579e54f' 
  AND token = 'rj3Tt4QVt3A6BLMYu7aqQ2xBc6vNu31SEuyxzud+ZIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}