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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3601bd4cb5afea4ff42cbfea0237559e9d60b35a1ad00f7623b49ca2370d8387' 
  AND token = 'xJD87iaO6YdMfugF1mNWjKO8QQcWWMPT4IAD/hRrj3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}