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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d081ec87000e3ec3da3cf6a9208a9e1d6ac2bb226256dfbf1cc7ea24db07d17' 
  AND token = '2JcJ9Zo9sQ5gfzQJizhe00RFYtMoerAslYvhcHbirF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}