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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33afd06687ab66f360fa1e46e782d7f52daaa8029d5effa9d1291d7a92c53224' 
  AND token = '2J+4IZNiwEesxg80kd4dgCGIPgRcOgnQZv/AkXzV3zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}