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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '321355eeab574942fc9120902396abf937e6d9d620cb4b4bb4207e9a4110c516' 
  AND token = 'QSKTsSUllbIN/t1LUkKK4yhieaynFKAHV4s2rAFqYog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}