SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4db557ff36146cca0ba8a8262dc1d0800493c05f1950dcbda2642aa8f9c257d' 
  AND token = 'MyEBKFgpgtSa/tWWp7Np+UzEgr++Qxj7ppYyVEQZRug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}