SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2a3200add792d43acdc91fa0a495cc9da2a3321b151b0a23c2cce7710d0499c' 
  AND token = 'xp/tifngahZhzXEjX+oCKzc8dVlIu+VyRY8CYZz14Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}