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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b325b13f6bd3da2824dd74219331a95c8c391247555bb205552e53d4ca37cbf4' 
  AND token = 'A2QttKWim3P2zLniqjxpAoB4bkvDeosCmokdaRNC8+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}