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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721f89bcad9fe4355163ae65797272028b8e8a68e267c4ff74e39ff2597bc1cf' 
  AND token = 'qszkKzw7mBIr81/M6TrzVAd36bCL72ilz9qP6ONl9Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}