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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '856b33471592ccf5046a9027ec01ac4e52d9d520b0397ed7d30f15b1d9ce5377' 
  AND token = '9pUM4zGjWmhRJga2nF3MawmAsg96IAWjp+jGAVR8gF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}