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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3b7fa7434a827f6cd35b68b848cce59d7ef13744ed5ef237ba231d9780aaf16' 
  AND token = '4nwk8dic1a+pGdAZluAWlZv5Mf1hGn+BE3QpIGtIXk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}