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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d578afb1e697b8e34e76c5386ee654fda89826fa4e51ef79927a52c05470ee2' 
  AND token = 'LTyQwgj3XAi2w4+si7NekNSb0XZbIQQa8LMZ0Y/kajM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}