SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133359a4e8723d67652d68d3852cf9149aa282eb330ecdf699f76292d27cadcf' 
  AND token = '6l7uslnVoBlSZTQDSac5+w3isIDOuQEuljZBa3pIXd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}