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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ba6eea13df31adab59f1cb18f10bf4f4d5f3adaf7324799c9422147e266fefa' 
  AND token = 'ox8q8XUxyXMu+ZBGpEEIwdsBRxONJnm7f1yzPQ++NlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}