SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d50f67b0dffbb2e0996949b1e27c4c6ebe79461384335bfa6f91b653235ca05' 
  AND token = 'GgfTYIIBiQs6+0jKJtZrhlTvgH94bkA+DY7tX8ita6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}