SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dce5261166bd3cda56ed28673f8db82abeb40ce31887ffe46f84066e4f99ae1' 
  AND token = 'Utv3C4F2pQfvTGrymOiN5i+tLnifnvG7vmUtJb2Z3qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}