SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b3a40d9fdce40302a1cb6c6e49b2ceca919a5462aafca8f0346d3c8436d37d2' 
  AND token = 'Wtah5egRZ84cNVWrAxfg/+FEOta77ShpoLA8ufSJJ60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}