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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351262d1a613b50a30f819fa1450e56adf5f2b4960e32bf684d87306ff50a9e9' 
  AND token = 'BmTwvp92j1DdLWc9dk+CWVDQJLPF9R8YYFtaFr2NRig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}