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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e7f8e9c6c82dac767544a21fb5267472981fdd1738f1bdb64d73ad24b5efcc' 
  AND token = 'GykHF3KW3PaZViZdVpexYfW6NkbBtx/KuQdCdyBbUUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}