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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c7ef66b0c132c8be02a548a580a851af4325f45bbf13c8635b16491578dfc91' 
  AND token = '/O4Cf0Qsb3kVOjhAcqPC8LjkevxZws85s31Fg7EFnUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}