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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753fb7464366a6e16e999a935ac8eec291fbcbc542bc9fd2c8d364e5ea3ad91a' 
  AND token = 'XecW1AMizI21+tSkTpA4n0nGg8GE2sF85kKJePy7ivE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}