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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3943888b8e2cade3e1b494bd0949a7761ad2fa14743372770ee34f001111c9' 
  AND token = '2udj0U9O5vLFw5lkhay+JwLeAp9iF5KDE+wlwVJP55I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}