SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72c19e8ca767a59839b8beb8a68c2ce3449ce59fa9034d9443d0d2c383fb57a' 
  AND token = '09+zMDJGBbixLf2QW0s13eccg8liDfXx9/+yH/90v0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}