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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89157985c43e13bd5828658d0a07657ea8c07380890bd853b812c380e2f1e1ff' 
  AND token = 'aDsWCmYs/eT16Jv+KTf8YXuXQ1+FRJ35QMr57zzESdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}