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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '394b48cd4da11954a18fb7fe3eabe1fc2426238736e34d6e129b5fbf3ffcc45f' 
  AND token = 'acqw6+SacDhfe5mv0zBscBU8wbWIEXvhfJtA+a5HTbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}