SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66150717a7b8c1b8529de792f9eeeab2fdceb53d519e3a032f186dbca60a85f1' 
  AND token = '0dqrdbTMz6/vTCCPAXBm05TmsE2HHrTQeH8YaW6/uUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}