SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dff614a50eb19205a4bb297a111ffd1eb402ead2ac4803dc7356959ebe29b10' 
  AND token = 'BFiUT53hwTZ7Mo9ZAMq2NIyPcUJ4r4vEWHg7FiiiKfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}