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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cdbd2a7ee4ff7327adc78d599ee670c5d034f2d24820a55dae35d06be1d677c' 
  AND token = 'mbRJ4XQexAeODVxtDiejRZnIwY6PHF01IjpwKxtyoc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}