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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0d6195cf4dd09ca955240b81f41a63cb69f00a537668e30b0ee68e7dae1fd12' 
  AND token = '+mpRrXU3E6iKH7qZ+tB+Eq98OcS2T4xmAKrhAuOk3v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}