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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3ca21f8617deadc133a391fd8fed7fad3dfc9cfc2b4261495f6eb9140312d1' 
  AND token = 'kiIz81HE2wbQKIZKrmbzaaowHz6ebKv/xA8dXr62Zz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}