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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e7d9004fe2d180a442c8a7187acb3648db8cb2ce2218c87585e5e23693dd6b' 
  AND token = 'KRqO6jvs39cDWAGTS3B4xIK8soNzGfR6GZIlkpN0TuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}