SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac372ff491155e0a1a97929e6fceb17df6f09c53f5185aad10a05380d0136e3' 
  AND token = '4q0w1u8NKSTTsctAL0qPHhIW6FqsfaE2Q4Nm7a3t4xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}