SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe14bf0431c6e05c920e824a7f34e37d18db2555c0a7649d662788ca5587768b' 
  AND token = 'UD2BEKn8D1WaoQ8NJ6WnOxxUufuysXrWsFAZ55GeKXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}