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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ae9d86eee830ba696ab007a8e4d2b427230323d30da9bb10d1ad53f1d6406a' 
  AND token = 'axmOBVkfL3hl5oKFBCr42vG81kv/oJLaD3khySPg50M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}