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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9db157a3eaecc0a4287e0e87bf0f51cb668f7f8d65b01be46fd86589a2c20516' 
  AND token = 'I1uSGCy2aeMRPxhOq944AFCjuMmhV9jIvi0IyPIYShM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}