SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006536fc36ff62099583b51cc95bad9d3954b0d91c2b3f5ea87f89d2528e0a58' 
  AND token = '+MEX2tN/gZ2cnOD4zYiAqCfM8t0YfDHOMSmEhJf9SUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}