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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018024a485df546d130d95686b64b53bed8ea46e36a21a3d37bc341b273b3dfd' 
  AND token = 'Bddn4cqXfERi+PvbjjfrrHzvlzhxM2J82NMcZ/rKxRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}