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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e36bcaa8f2620c1d93e28c5545c419dcf6be56d7e625b858151736c4caf7a0' 
  AND token = 'ljyWVn7j98s1QqsWzkMQ8IPeMGXVJPEZMHPa6kLZyBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}